Processing Of Mesoporous Hydroxyapatite Using Cetyltrimethylammonium Bromide (CTAB) As A Porogen And Its Characterization

The present research attempt consists in the development of mesoporous hydroxyapatite using inexpensive ingredients using cetyltrimethylammonium bromide (CTAB) as template through a chemical-based hydrothermal method. Wide angle X-ray diffraction (XRD) reveals the formation of pure single-phased hydroxyapatite particles. Fourier transform infrared absorption spectroscopy (FTIR) and electron diffraction X-ray (EDX) studies show the stoichiometric formation of HAp particles. The formation of mesoporous HAp has been confirmed by low angle XRD and Brunauer–Emmett–Teller (BET) surface area analysis studies. Transmission electron microscopy (TEM) analysis divulges needle like acicular crystals of HAp particles with approximate size of 28-36 nm in diameter by 8294 nm in length. the hemocompatibility study shows that the material is highly hemocompatible. The cell viability study shows that the material is cytocompatible. The developed mesoporous hydroxyapatite material may be used in making a biocomposite, drug delivery and bone tissue engineering